202 research outputs found

    La otra cara de la terapia: la vida personal del psicoterapeuta

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    El presente artículo intenta mostrar, de diversas formas, que si el profesional en psicología se realiza autoanálisis constantes e incrementa su autoconocimiento, su capacidad de resolver conflictos propios y su calidad de vida, se aumentará la eficacia de la terapia. Además, se exponen algunos argumentos para sustentar la tesis de que la relación terapéutica, de ninguna manera es algo mecánico e inamovible, sino en cambio, un fenómeno flexible que el clínico debe utilizar para el beneficio del proceso terapéutico

    Niños y niñas: futuros posibles; sujetos que construyen nuevas realidades

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    En este artículo se pretende realizar una reflexión crítica frente a la perspectiva e ideología en la que los estudios científicos han abordado históricamente a los niños y niñas y realiza una propuesta con la intención de dar un giro a esta visión, promoviendo la idea de que los niños y niñas son agentes de cambio, pueden realizar acciones políticas, tienen sus propias formas de habitar en el mundo y también sus propias potencialidades para transformarlo

    Antibiotics prescription habits of Spanish endodontists : impact of the ESE awareness campaign and position statement

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    The inadequate use of antibiotics by dentists can contribute to antibiotic resistance. The European Society of Endodontology (ESE) has published a scientific evidence-based position on antibiotic use in endodontic infections. The aim of thi

    Young Nursing Student’s Knowledge and Attitudes about Contraceptive Methods

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    We would like to thank all the nursing students who voluntarily participated in this studyPurpose: Adolescence is considered a period in which individuals are particularly at risk of negative consequences related to sexual health. Increased knowledge levels have traditionally been used as an indicator of the effectiveness of educational programs, but attitudes are not addressed and are a key element for the success of such programs. The aim of this study is to determine the level of knowledge and attitudes toward the use of contraceptive methods among nursing students. A multicenter cross-sectional study was carried out. In total, 2914 university students (aged 18–25 years) enrolled in the study. Participants completed two validated scales to measure knowledge level and attitudes toward contraceptive use. Nursing degree students who received training about contraceptives obtained a success rate of over 70%, compared to 15.3% among students who had not received such training (p < 0.001). The mean attitude score was 43.45 points (10–50), but there were no significant differences in terms of student training (p = 0.435), although they were significantly higher among students who used contraceptives at first or last sexual intercourse (p < 0.001). There was a significant weak correlation between the level of knowledge and attitudes toward the use of contraceptives. An adequate level of knowledge about sexuality and contraceptive methods does not correspond to positive attitudes toward their use, although having an excellent attitude toward contraceptive use is related to their use during youth and adolescence

    Relatório de condições sistemáticas de pacientes adultos. : Faculdade de Odontologia, Universidade de Antioquia, 2011

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    Introduction: The goal of this research project was to determine the prevalence and concordance of reports of a group of systemic conditions by means of Dental/Medical Records (mrs) and telephonic surveys (TS) in patients consulting at two adults’ clinics at the Faculty of Dentistry of the University of Antioquia. Methods: Cross-sectional study (n = 104). We evaluated clinical records and registered the 10 most frequent systemic diseases according to the epidemiological data in Medellin (Colombia). We used TS to corroborate previous information on the mrs. We measured the prevalence of the diseases and determined a concordance level between the results of mr and ts through a kappa index with a 95% confidence interval (95%CI); according to different variables. Results: The most prevalent systemic disease was ocular disease (58% ts and 30% mr, statistically significant p &lt; 0.001) and the less prevalent one was hyperthyroidism (3% mr and 5% ts, no statistically significant). Kappa analyses showed the weakest concordance in the case of hyperthyroidism (0.22; 95%CI -0.38-0.82) and in case of ocular disease (0.37; 95%ci 0.20- 0.72). Variability in the prevalence and kappa indexes was observed related to gender, type of clinic and age interval. Conclusions: Variations in the reported prevalence between the mr and ts were found. This situation may be explained as originating in difficulties completing medical antecedents, which cause an underreporting in the MR.Introducción: el objetivo de esta investigación fue determinar la prevalencia y la concordancia en el reporte de condiciones sistémicas entre la historia clínica odontológica (hc) y la entrevista telefónica (et), en los pacientes que asisten a dos clínicas del adulto de la Facultad de Odontología de la Universidad de Antioquia. Métodos: estudio transversal (n = 104). Se evaluaron las hc y se registraron las diez condiciones sistémicas más frecuentes según registros epidemiológicos de Medellín. Se realizó et para verificar información de las hc. Se calcularon prevalencias y el nivel de concordancia entre resultados de la hc y la et mediante el índice kappa y su intervalo de confianza al 95% (ic95%), según variables. Resultados: la condición sistémica más prevalente fue la enfermedad ocular (58% según et y 30% según hc y diferencias significativas p &lt; 0,001), y la menos prevalente fue el hipertiroidismo (3% según hc y 5% según et, sin diferencias significativas). El análisis kappa mostró que las concordancias más débiles se presentaron para el hipertiroidismo (0,22; ic95%-0,38-0,82) y la enfermedad ocular (0,37; ic95% 0,20-0,72). Se evidenciaron variaciones en los índices de concordancia de acuerdo con sexo, clínica y edad. Conclusiones: existen variaciones en las prevalencias reportadas por hc y por et debidas a dificultades a la hora de diligenciar los antecedentes médicos personales, que produjeron un subregistro en la hc. &nbsp;Introdução: o objetivo desta pesquisa foi determinar a prevalência e a concordância no relatório de condições sistêmicas entre o prontuário médico odontológico e a entrevista telefônica (et) nos pacientes que vão a duas clínicas do adulto da Faculdade de Odontologia da Universidade de Antioquia. Métodos: estudo transversal (n = 104). Avaliaram-se os prontuários e se registraram as dez condições sistêmicas mais frequentes segundo registros epidemiológicos de Medellín. Realizou-se et para verificar informação dos prontuários. Calcularam-se prevalências e o nível de concordância entre resultados do prontuário e da et mediante o índice kappa e seu intervalo de confiança a 95% (ic95%), segundo variáveis. Resultados: a condição sistêmica mais prevalente foi a doença ocular (58% segundo et e 30% segundo prontuários e diferenças significativas p &lt; 0,001), e a menos prevalente foi o hipertireoidismo (3% segundo prontuários e 5% segundo et, sem diferenças significativas). A análise kappa mostrou que as concordâncias mais fracas se apresentaram para o hipertireoidismo (0,22; ic95%-0,38-0,82) e a doença ocular (0,37; ic95%0,20-0,72). Evidenciaram- se variações nos índices de concordância de acordo com sexo, clínica e idade. Conclusões: existem variações nas prevalências relatadas pelo prontuário e pela et devidas a dificuldades na hora de diligenciar os antecedentes médicos pessoais, que produziram um sub-registro no prontuário

    Young Nursing Student’s Knowledge and Attitudes about Contraceptive Methods

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    Purpose: Adolescence is considered a period in which individuals are particularly at risk of negative consequences related to sexual health. Increased knowledge levels have traditionally been used as an indicator of the effectiveness of educational programs, but attitudes are not addressed and are a key element for the success of such programs. The aim of this study is to determine the level of knowledge and attitudes toward the use of contraceptive methods among nursing students. A multicenter cross-sectional study was carried out. In total, 2914 university students (aged 18–25 years) enrolled in the study. Participants completed two validated scales to measure knowledge level and attitudes toward contraceptive use. Nursing degree students who received training about contraceptives obtained a success rate of over 70%, compared to 15.3% among students who had not received such training (p < 0.001). The mean attitude score was 43.45 points (10–50), but there were no significant differences in terms of student training (p = 0.435), although they were significantly higher among students who used contraceptives at first or last sexual intercourse (p < 0.001). There was a significant weak correlation between the level of knowledge and attitudes toward the use of contraceptives. An adequate level of knowledge about sexuality and contraceptive methods does not correspond to positive attitudes toward their use, although having an excellent attitude toward contraceptive use is related to their use during youth and adolescence

    NGS-Based Molecular Karyotyping of Multiple Myeloma: Results from the GEM12 Clinical Trial

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    Simple Summary Multiple Myeloma (MM) is considered an incurable chronic disease, which prognosis depends on the presence of different genomic alterations. To accomplish a complete molecular diagnosis in a single essay, we have designed and validated a capture-based NGS approach to reliably identify pathogenic mutations (SNVs and indels), genomic alterations (CNVs and chromosomic translocations), and IGH rearrangements. We have observed a good correlation of the results obtained using our capture panel with data obtained by both FISH and WES techniques. In this study, the molecular classification performed using our approach was significantly associated with the stratification and outcome of MM patients. Additionally, this panel has been proven to detect specific IGH rearrangements that could be used as biomarkers in patient follow-ups through minimal residual disease (MRD) assays. In conclusion, we think that MM patients could benefit from the use of this capture-based NGS approach with a more accurate, single-essay molecular diagnosis. Next-generation sequencing (NGS) has greatly improved our ability to detect the genomic aberrations occurring in multiple myeloma (MM); however, its transfer to routine clinical labs and its validation in clinical trials remains to be established. We designed a capture-based NGS targeted panel to identify, in a single assay, known genetic alterations for the prognostic stratification of MM. The NGS panel was designed for the simultaneous study of single nucleotide and copy number variations, insertions and deletions, chromosomal translocations and V(D)J rearrangements. The panel was validated using a cohort of 149 MM patients enrolled in the GEM2012MENOS65 clinical trial. The results showed great global accuracy, with positive and negative predictive values close to 90% when compared with available data from fluorescence in situ hybridization and whole-exome sequencing. While the treatments used in the clinical trial showed high efficacy, patients defined as high-risk by the panel had shorter progression-free survival (p = 0.0015). As expected, the mutational status of TP53 was significant in predicting patient outcomes (p = 0.021). The NGS panel also efficiently detected clonal IGH rearrangements in 81% of patients. In conclusion, molecular karyotyping using a targeted NGS panel can identify relevant prognostic chromosomal abnormalities and translocations for the clinical management of MM patients

    Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

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    A measurement of the cosmic-ray spectrum for energies exceeding 4×10184{\times}10^{18} eV is presented, which is based on the analysis of showers with zenith angles greater than 6060^{\circ} detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above 5.3×10185.3{\times}10^{18} eV, the "ankle", the flux can be described by a power law EγE^{-\gamma} with index γ=2.70±0.02(stat)±0.1(sys)\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)} followed by a smooth suppression region. For the energy (EsE_\text{s}) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find Es=(5.12±0.25(stat)1.2+1.0(sys))×1019E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19} eV.Comment: Replaced with published version. Added journal reference and DO

    Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

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    The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO
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